Missouri Cannabis Market History
From medical launch to $1.46 billion market — the story of Missouri cannabis in data.
2019
Medical Program Launches
Missouri begins issuing medical cannabis facility licenses after voters approve Amendment 2 in 2018.
2020
First Dispensaries Open
First medical dispensaries begin serving patients. CLOVR becomes first manufacturer approved to operate.
2021
Medical Market Grows
Illicit Gardens becomes #1 best-selling brand (BDSA). Medical sales reach $209.75M.
$209.75M
2022
Adult-Use Legalization
November: Voters approve Amendment 3 legalizing adult-use cannabis. Medical sales estimated at $360M.
$360M
Feb 2023
Adult-Use Sales Begin
Missouri launches adult-use sales. Market explodes beyond all projections. Good Day Farm and Codes Cannabis emerge as top brands.
2023
First Full Year
Combined adult-use and medical sales reach $1.3 billion in the first full year. Missouri becomes 6th largest cannabis market in the US.
$1.3B
2024
Market Maturity
Total sales reach $1.46B. Good Day Farm becomes #1 brand at $27M in Q2 alone. $244.9M in tax revenue generated. 21,800 Missourians employed.
$1.46B
Jan 2026
Illicit ESOP
S1 Enterprises (Illicit Gardens) becomes employee-owned — largest ESOP in cannabis history.
2028
Market Projection
Industry projects Missouri cannabis market to reach $1.73 billion.
$1.73B

