Missouri Medical Cannabis
How to get a medical cannabis card in Missouri, who qualifies, and the benefits over recreational
Last updated: March 2026
Educational purposes only. This content does not constitute legal, medical, or professional advice. Cannabis laws change frequently — always verify with official Missouri DCR sources or a qualified professional.
Qualifying Conditions
- Cancer
- Epilepsy / seizures
- Glaucoma
- Intractable migraines
- Chronic severe pain
- Persistent muscle spasms (including MS)
- Crohn's disease
- Ulcerative colitis
- Agitation of Alzheimer's
- HIV / AIDS
- PTSD
- ALS
- Hepatitis C
- Autism
- Sickle cell anemia
- Terminal illness
- Any other chronic or debilitating condition
Step-by-Step: How to Get Your Card
Consult a licensed Missouri physician
Schedule an appointment with a physician who can evaluate your qualifying condition.
Physician certifies your condition
The physician submits a certification to the state confirming you have a qualifying condition.
Create your state account
Register at mo.gov/myDHSSportal to begin your application.
Submit application + certification
Upload your physician certification, ID, and complete the application form.
Pay the $25 application fee
One-time fee. Cards are valid for 3 years.
Receive your card
Typically processed within 30 days. Card is valid for 3 years from issue date.
Medical vs Recreational Comparison
| Feature | Medical | Recreational |
|---|---|---|
| Possession (on person) | 6 oz | 3 oz |
| Possession (at home) | 8 oz | 6 oz |
| Tax rate | Lower (no 6% rec tax) | Standard + 6% |
| Home grow | 6 plants | 6 plants |
| Minimum age | 18+ | 21+ |
| Card cost | $25 / 3 years | N/A |
Caregiver Program
- Adults can serve as caregiver for up to 3 patients
- Caregiver can purchase and possess on patient's behalf
- Caregiver must be registered with DCR
- Caregivers can also cultivate plants for their patients
Resources
- Missouri DHSS Medical Cannabis Portal: mo.gov/myDHSSportal
- Division of Cannabis Regulation: cannabis.mo.gov
Related Resources
Disclaimer: The information on this page is for educational purposes only and does not constitute legal, medical, or professional advice. Cannabis laws and regulations change frequently. Always verify current information with official Missouri state sources or consult a qualified professional.

